供应科研试剂 阳离子脂质体 SM-102 2089251-47-6

SM-102 CAS No.: 2089251-47-6 十七烷-9-基-8-((2-羟乙基))6-氧代-6-((十一烷氧基)己基)氨基)辛酸酯； 辛酸8-((2-羟乙基)(6-氧代-6-((十一烷氧基)己基)氨基)1-辛基壬基酯 Heptadecan-9-yl 8-((2-hydroxyethyl)(6-oxo-6-(undecyloxy) hexyl) amino) octanoate; Octanoic acid, 8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]-, 1-octylnonyl ester 分子式: C44H87NO5 分子量: 710.17 沸点?725.8±50.0 °C 密度?0.925±0.06 g/cm3 酸度系数(pKa)14.67±0.10 SM-102 是一种可电离的氨基阳离子脂质，可用于形成脂质纳米颗粒 (LNPs)，递送mRNA核酸药物（如：疫苗）。 SM-102 is an ionizable amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles.1 Administration of luciferase mRNA in SM-102-containing lipid nanoparticles induces hepatic luciferase expression in mice. Formulations containing SM-102 have been used in the development of lipid nanoparticles for delivery of mRNA-based vaccines.